Psoriasis is traditionally considered a non-itchy skin disease. It seems that itch is an underestimated, and therefore undertreated aspect of psoriasis. MedDRA version: 19.1 Level: PT Classification code 10037153 Term: Psoriasis System Organ Class: 10040785 - Skin and subcutaneous tissue disorders
Conditions
Interventions
Trade Name: Dexeryl
Product Name: Dexeryl® crème
Pharmaceutical Form: Cream
INN or Proposed INN: Glycerol
Other descriptive name: GLYCEROL
Concentration unit: % percent
Concentration type: equal
Conce
Sponsors
UZ Brussel
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Psoriasis patients =18 years old Any complaints of pruritus in the last week, with a VAS pruritus >5 Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 15 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 5
Exclusion criteria
Exclusion criteria: Unable to read IC Unable or unwilling to applicate creams according to protocol Unwilling to stop topicals during 10 days Recent start of systemic therapy for psoriasis (upto the investigators discretion)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Our aim is to measure the effects of (cheap) indifferent topical treatments.;Secondary Objective: To weigh the amount of used cream.;Primary end point(s): Reduction in itch (VAS-score) during and after application of Dexeryl cream (through diary). Evolution of itch after stop Dexeryl.;Timepoint(s) of evaluation of this end point: - Daily (diary) - Final evaluation at day 20 | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Look into a relation of itch-evolution and amount of used cream.;Timepoint(s) of evaluation of this end point: day 20 | — |
Countries
Belgium
Contacts
Public ContactTom Hillary
UZ Brussel
Outcome results
None listed