Does oxytocin influence consciousness and suggestibility?

Effects of oxytocin on suggestibility and consciousness - Oxytocin and sensed presence

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2016-004826-40-SE

Enrollment

120

Registered

2016-12-21

Start date

2017-02-17

Completion date

Unknown

Last updated

2020-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

There are no medical conditions or diseases under investigation MedDRA version: 19.1 Level: PT Classification code 10033334 Term: Oxytocin normal System Organ Class: 10022891 - Investigations

Interventions

Trade Name: Syntocinon Product Name: Syntocinon Pharmaceutical Form: Nasal spray, solution INN or Proposed INN: OXYTOCIN CAS Number: 50-56-6 Other descriptive name: Oxytocin Concentration unit: IU int

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Healthy women and men 18-30 years old - Fluent SWedish - Right-handed - Live in the Stockholm area Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 120 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: - Pregnacy - Breastfeeding - Nasal allergies - Sesame or nuts allergy - Any known neurological, visual, and auditory impairment - Use of medication (except oral contraceptives) - Drug or alcohol abuse - Psychiatric disorder - Nasal disease or obstruction - Smoking - Claustrophobia (fear to close rooms/spaces - Fear to dark rooms/spaces

Design outcomes

Primary

Measure	Time frame
Main Objective: Examine whether OXT facilitates the occurrence and affects the quality of spiritual experiences and the sensed presence of a sentient being.;Secondary Objective: - Determine whether oxytocin receptor polymorphism contributes to spiritual experience and the sensed presence of a sentient being, either in itself or in combination with exteroceptive oxytocin administration. - Study whether individual differences in personality dispositions (attachment, propensities for ”absorption”, philosophy of life) further contribute to the outcomes.;Primary end point(s): Descriptions of sensory experiences during deprivation (dark room,no noise). The descriptions will be written by the participants themselves.;Timepoint(s) of evaluation of this end point: 45 minutes after administration of oxytocin or placebo	—

Measure

Time frame

Main Objective: Examine whether OXT facilitates the occurrence and affects the quality of spiritual experiences and the sensed presence of a sentient being.;Secondary Objective: - Determine whether oxytocin receptor polymorphism contributes to spiritual experience and the sensed presence of a sentient being, either in itself or in combination with exteroceptive oxytocin administration. - Study whether individual differences in personality dispositions (attachment, propensities for ”absorption”, philosophy of life) further contribute to the outcomes.;Primary end point(s): Descriptions of sensory experiences during deprivation (dark room,no noise). The descriptions will be written by the participants themselves.;Timepoint(s) of evaluation of this end point: 45 minutes after administration of oxytocin or placebo

—

Secondary

Measure	Time frame
Secondary end point(s): Self-reported inventories that focus on personality, affiliation, philosophical and spiritual experiences;Timepoint(s) of evaluation of this end point: After the description of sensory deprivation	—

Countries

Sweden

Contacts

Public ContactPehr Granqvist

Department of Psychology, Stockholm University

pehr.granqvist@psychology.su.se004608163681

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026