Can Insuline improve the healing of dental implants?

Status

Not yet recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2016-002112-41-SE

Enrollment

Unknown

Registered

2016-05-30

Start date

2016-07-16

Completion date

Unknown

Last updated

2016-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missing teeth

Interventions

Trade Name: Humulin Regular Product Name: Humulin Regular Pharmaceutical Form: Concentrate for solution for injection Pharmaceutical form of the placebo: Concentrate and solvent for solution for injec

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - At least 18 years. - Partial or complete missing teeth. - Healthy patients or patients with moderate systemic disease (ASA I and II). Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 20 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: - Persons who are not eligible because of language problems, substance abuse, dementia or other serious illness. - Patients with lack of bone tissue which require bone graft to perform treatment (Cawood & Howell Class III to V). - Diabetics. - Previous radiotherapy in maxillofacial area. - Patient with severe systemic disease (ASA> III). - Hypersensitivity to the active substance or to any of the excipients.

Design outcomes

Primary

Measure	Time frame
Main Objective: The main objective is to asses if Insuline can improve the healing of dental implants.;Secondary Objective: The secondary objective to see if the bone density around the dental implantat treated with Insuline increases?;Primary end point(s): Bone healing measured by Resonance frequency measurement.;Timepoint(s) of evaluation of this end point: The bone density measured by Cone Beam Computed Tomography.	—

Measure

Time frame

Main Objective: The main objective is to asses if Insuline can improve the healing of dental implants.;Secondary Objective: The secondary objective to see if the bone density around the dental implantat treated with Insuline increases?;Primary end point(s): Bone healing measured by Resonance frequency measurement.;Timepoint(s) of evaluation of this end point: The bone density measured by Cone Beam Computed Tomography.

—

Secondary

Measure	Time frame
Secondary end point(s): 1, Peroperative, 8 weeks and three years after the operation.;Timepoint(s) of evaluation of this end point: 2, Preoperative, 8 weeks and three years after the operation.	—

Countries

Sweden

Contacts

Public ContactKäkkliniken, Universitetssjukhuset

Region Östergötland

Jahan.Abtahi@regionostergotland.se0046101038551

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026