Transversus abdominis plane blok, continous systemic administration of lidocain and patient controlled intravenous morphine - 3 methods for postoperative pain control after laparoscopic colorectal surgery: a randomised comparative trial

Transversus abdominis plane blok, continous systemic administration of lidocain and patient controlled intravenous morphine - 3 methods for postoperative pain control after laparoscopic colorectal surgery: a randomised comparative trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2014-001499-73-BE

Enrollment

125

Registered

2014-06-13

Start date

2014-07-31

Completion date

Unknown

Last updated

2021-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain MedDRA version: 17.1 Level: LLT Classification code 10036236 Term: Postoperative pain relief System Organ Class: 100000004865

Interventions

Trade Name: linisol 1% Product Name: linisol 1% Product Code: NA Pharmaceutical Form: Injection INN or Proposed INN: linisol Other descriptive name: LIDOCAINE 1% Concentration unit: % percent Concentr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA 1,2 &3 laparoscopic colorectal surgery patients between 18 and 75 years of age written informed consent Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 85 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 40

Exclusion criteria

Exclusion criteria: allergic to lidocain chronic use of opiods liver insufficiency (bili total >= 2 mg/dl) renal insufficiency (eGFR<= 60 ml/min/1.73m**2) epilepsy morbide obesity sleep apneu cardiac dysrhythmia mental retardation

Design outcomes

Primary

Measure	Time frame
Main Objective: Does a TAP-block offers superior analgesia in comparison with systemic administation of linisol after laparoscopic colo-rectal surgery;Secondary Objective: incidence of post-operative complications;Primary end point(s): Does the use of a TAP block offers superior analgesia compared with systemic linisol administration and patient controlled intravenous administration of morphine or patient controlled intravenous administration of morphine alone;Timepoint(s) of evaluation of this end point: morphine consumption on postoperative day1, day 2 and day 3	—

Measure

Time frame

Main Objective: Does a TAP-block offers superior analgesia in comparison with systemic administation of linisol after laparoscopic colo-rectal surgery;Secondary Objective: incidence of post-operative complications;Primary end point(s): Does the use of a TAP block offers superior analgesia compared with systemic linisol administration and patient controlled intravenous administration of morphine or patient controlled intravenous administration of morphine alone;Timepoint(s) of evaluation of this end point: morphine consumption on postoperative day1, day 2 and day 3

—

Secondary

Measure	Time frame
Secondary end point(s): - the recovery of bowel movement -incidence of post operative nausea and vomiting, - length of hospitalization - in- hospital morbidity - the inflammatory respons;Timepoint(s) of evaluation of this end point: post operative day 1, 2 , 3 and at discharge	—

Countries

Belgium

Contacts

Public ContactAnesthesie Research

Univeristy Hospitals Leuven

christel.huygens@uzleuven.be+32 16344620

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026