pornographic addiction
Conditions
Interventions
Product Name: [11C]-raclopride
Product Code: [11C]-raclopride
Pharmaceutical Form: Radiopharmaceutical precursor, solution
Sponsors
University Medical Center Groningen
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: - male sex - age between 18 and 45 - a modified CIUS score>3 Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 28 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: - lifetime DSM-IV axis I disorder, - drug dependence or abuse; including alcohol (i.e. drinking more than 30 drinks per month or any illicit drug use during the past 30 days); - active medical condition; - treatment in the last 6 months with antidepressants, neuroleptics, sedative hypnotics, glucocorticoids, appetite suppressants, sex hormone, opiate or dopamine medications - use of psychoactive medications within the past 30 days; - lifetime history of seizure disorder or closed head trauma; - participation in a scientific research study (<1 year) involving radiation - Contra-indications for MRI-scanning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The primary objective is to determine the dopamine D2 receptor availability and dopaminergic function in subjects with pornographic addiction and to compare the availability with control subjects.;Secondary Objective: The secondary objectives are to correlate the dopamine D2 receptor availability to prefrontal cerebral blood flow, the severity of addiction as measured by the Compulsive Internet Use Scale (CIUS), and personality traits of impulsivity and sensation seeking.;Primary end point(s): n/a;Timepoint(s) of evaluation of this end point: n/a | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): n/a;Timepoint(s) of evaluation of this end point: n/a | — |
Countries
Netherlands
Contacts
Public ContactClinical Trial Information
University Medical Center Groningen
Outcome results
None listed