Evaluation of muscle function recovery after deep neuromuscular blockade by acceleromyography of the adductor pollicis or diaphragmatic echography: comparison between sugammadex and neostigmine

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2013-004787-62-IT

Enrollment

Registered

2014-06-18

Start date

2014-11-26

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle function recovery post neuromuscoular blockade MedDRA version: 19.1 Level: PT Classification code 10057286 Term: Neuromuscular blockade reversal System Organ Class: 10042613 - Surgical and medical procedures

Interventions

Trade Name: Bridion Product Name: Bridion 100 mg/ml Pharmaceutical Form: Solution for injection INN or Proposed INN: Bridion Other descriptive name: SUGAMMADEX Concentration unit: mg/ml milligram(s)/m

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Patients' informed consent • Age between 18 and 80 years • Class ASA I e II Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 40 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 20

Exclusion criteria

Exclusion criteria: Hepatic or renal insufficiency Emergency or urgency intervention

Design outcomes

Primary

Measure	Time frame
Main Objective: To evaluate by ecography the effect of sugammadex vs. neostigmine in the recovery of diaphragmatic function after deep neuromuscular blockade;Secondary Objective: Reduction adverse events after surgical intervention.;Primary end point(s): reduction of curarization;Timepoint(s) of evaluation of this end point: 30 minutes	—

Secondary

Measure	Time frame
Secondary end point(s): post-intervention adverse events.;Timepoint(s) of evaluation of this end point: 24 hours	—

Countries

Italy

Contacts

Public ContactSOD Anestesia DAI Organi di Senso

Azienda Ospedaliero Universitaria Careggi, Dipartimento Organi di Senso, Otorinolaringoiatria

chiara.adembri@unifi.it00390554271101

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026