The effect of strong saline on blood electrolytes, acid-base balance and hormones that regulate blood pressure

The effect of hypertonic saline on blood electrolytes, acid-base balance and hormones that regulate blood pressure

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2013-004466-34-FI

Enrollment

Registered

2013-12-30

Start date

2014-02-25

Completion date

Unknown

Last updated

2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elevated intraocular pressure

Interventions

Trade Name: Natriumklorid Braun 234 mg/ml inf Product Name: Natriumklorid Braun 234 mg/ml inf Pharmaceutical Form: Infusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Good health condition Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 14 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 14

Exclusion criteria

Exclusion criteria: Oral acetazolamide medication, age under 25 years, age higher than 80 years, kidney failure, heart failure, dementia, other medical condition that markedly decreases patients physical condition

Design outcomes

Primary

Measure	Time frame
Main Objective: To study the safety of intravenous hypertonic saline in reducing intraocular pressure;Secondary Objective: Not applicable;Primary end point(s): Blood samples after hypertonic saline;Timepoint(s) of evaluation of this end point: 10, 20, 60 and 120 minutes	—

Secondary

Measure	Time frame
Secondary end point(s): Blood pressure and pulse;Timepoint(s) of evaluation of this end point: 10, 20, 60 and 120 minutes	—

Countries

Finland

Contacts

Public ContactDepartment of Ophthalmology

Helsinki University Central Hospital

+358947173161

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026