Uncomplicated urinary tract infection
Conditions
Interventions
Trade Name: Nitrofurantoin
Product Name: Nitrofurantoin
Pharmaceutical Form: Capsule
INN or Proposed INN: Nitrofurantoin
CAS Number: 67-20-9
Other descriptive name: NITROFURANTOIN
Concentration unit:
Sponsors
UMC St Radboud
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients having been prescribed nitrofurantoin by treating physician because suspicion of or proven urinary tract infection. - Age > 55 and =65 years) yes F.1.3.1 Number of subjects for this age range 5
Exclusion criteria
Exclusion criteria: - Treated with any antibiotics within 1 week of potential sampling period. - Known porphyria - Known allergic reaction or anaphylactic shock as a result of the consumption of nitrofurantoin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To determine the pharmacokinetics of orally administered nitrofurantoin in older hospitalised female patients with suspected or proven, active urinary tract infection. ;Secondary Objective: Not applicable;Primary end point(s): Nitrofurantoin plasma and urine levels.;Timepoint(s) of evaluation of this end point: At the analysis of all concentrations of nitrofurantoin in serum and urine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Not applicable;Timepoint(s) of evaluation of this end point: Not applicable | — |
Countries
Netherlands
Contacts
Public Contactcoordinating investigator
St Elisabeth hospital
Outcome results
None listed