Comparison of measured intravenously administered anesthetics in blood and in breath - pilot study

Offline monitoring of parallel concentrations of intravenously administered anesthetics, opiates and relaxants in breath and in blood during anesthesia - a pilot study - Expirtiva

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2013-004127-36-CZ

Enrollment

Unknown

Registered

2013-11-05

Start date

2013-12-19

Completion date

Unknown

Last updated

2016-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intravenous anaesthesia

Interventions

Pharmaceutical Form: Emulsion for injection/infusion Pharmaceutical Form: Powder for suspension for fish treatment Pharmaceutical Form: Solution for injection Pharmaceutical Form: Solution for inje

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA 1-2 Age 18-65 years Patient undergoing intravenous anaesthesia Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 50 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Contraindications to intravenous anaesthesia

Design outcomes

Primary

Measure	Time frame
Main Objective: pharmacokinetics;Secondary Objective: NA;Primary end point(s): Qualitative and quantitative anaylsis UHPLC-MS/MS;Timepoint(s) of evaluation of this end point: before anaesthesia, 3-5 minutes after dosing, 3-5 minutes after start of surgical intervention, next intervals 10-15 minutes	—

Secondary

Measure	Time frame
Secondary end point(s): other pharmacokinetics parameters;Timepoint(s) of evaluation of this end point: NA	—

Countries

Czech Republic

Contacts

Public ContactMichal Kroupa

Podripská nemocnice s poliklinikou, Roudnice n.L., s.r.o

mudrmichalkroupa@seznam.cz

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026