Asthma
Conditions
Interventions
Trade Name: Airomir
Pharmaceutical Form: Inhalation vapour
Sponsors
Medisch Spectrum Twente
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Clinical history of asthma symptoms. - Age 6 till 16 years old. - Ability to perform reproducible pulmonary function tests, i.e. coefficient of the predicted value variation in 3 of 5 consecutive measurements =65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: - Exacerbation in the last 4 weeks prior to the study (hospital admission or use of systemic corticosteroids). - Use of long acting bronchodilators 24 hours before testing. - Use of short acting bronchodilators 8 hours before testing. - Use of leukotriene antagonists 24 hours before testing. - Other pulmonary or cardiac disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To compare the clinical effect of 200µgr and 400µgr salbutamol inhaled with the forward leaning body posture compared to the standard body posture on the reversibility of pulmonary function variables.;Secondary Objective: To measure the possible discomfort body posture with the aid of a questionnaire partly based on the child VAS scores questionnaire and the body part discomfort scale questionnaire. To measure possible side effects of the salbutamol inhalation (palpitations, tremor, discomfort and rash) with the aid of a self designed questionnaire.;Primary end point(s): FEV1, VC, PEF, MEF25 and MEF75 reversibility (%);Timepoint(s) of evaluation of this end point: January 2014: recruiting children January 2014-March 2014: reversibility tests April 2014: Analysis data | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Possible discomfort body posture measured with VAS scores Possible side effects of the salbutamol inhalation: number of children complaining about palpitations, tremor, discomfort or rash. ;Timepoint(s) of evaluation of this end point: Same as timepoint(s) of evaluation of primary end point | — |
Countries
Netherlands
Contacts
Public Contactinvestigator/docter
Medisch Spectrum Twente
Outcome results
None listed