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The protective effect of one dose asthma medication against exercise asthma.

The protective effect of a single dose salbutamol against exercise induced inspiratory airflow obstruction in asthmatic children. - Inspiratory airflow

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
EU CTR
Registry ID
EUCTR2013-002769-20-NL
Enrollment
Unknown
Registered
2013-07-09
Start date
2013-09-04
Completion date
Unknown
Last updated
2013-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise induced bronchoconstriction

Interventions

Trade Name: Airomir Pharmaceutical Form: Inhalation vapour Pharmaceutical form of the placebo: Inhalation vapour Route of administration of the placebo: Inhalation use

Sponsors

Medisch Spectrum Twente
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Clinical history of EIB. - Age 8 till 16 years old. - Ability to run or jump and perform reproducible lung function tests, i.e. coefficient of the predicted value variation in 3 of 5 consecutive measurements =65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: - Exacerbation in the last 4 weeks prior to the ECT (hospital admission or use of systemic corticosteroids). - Use of long acting bronchodilators 24 hours before testing. - Use of short acting bronchodilators 8 hours before testing. - Use of leukotriene antagonists 24 hours before testing. - Other pulmonary or cardiac disorder.

Design outcomes

Primary

MeasureTime frame
Main Objective: Main objective of this study is to investigate if salbutamol protects against inspiratory airflow obstruction. ;Secondary Objective: Investigate the relation between the protective effect of salbutamol against inspiratory airflow obstruction and EIB. ;Primary end point(s): 12,5% reduction of MIF50 (Mid Inspiratory Flow);Timepoint(s) of evaluation of this end point: September 2013: recruiting children October 2013- March 2014: Exercise Challenge Tests April 2014 - May 2014: analysis data—

Secondary

MeasureTime frame
Secondary end point(s): not applicable;Timepoint(s) of evaluation of this end point: not applicable—

Countries

Netherlands

Contacts

Public ContactInvestigator / Docter

Medisch Spectrum Twente

r.visser@mst.nl0031534872310

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026