The effect of GnRH analog on the results of frozen-thawed embryo transfers.

GnRH analog as a luteal phase support in frozen-thawed embryo transfer cycles. A Pilot study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2013-000106-29-FI

Enrollment

240

Registered

2013-02-20

Start date

2013-03-19

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility MedDRA version: 14.1 Level: LLT Classification code 10042391 Term: Subfertility System Organ Class: 100000004872

Interventions

Trade Name: Gonapeptyl 0.1 mg/mi inj Pharmaceutical Form: Injection INN or Proposed INN: TRIPTORELIN ACETATE CAS Number: 140194-24-7

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 20 - 45 year old women coming to frozen thawed embryo transfer. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 240 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: The age of the woman over 42 year during the initial IVF/ICSI-treatment, from which the embryos derive. Abnormal uterus Known abnormality of karyotype of the woman or her partner Severe male factor as an exclusive reason for subfertillity Allergy for Gonapeptyl

Design outcomes

Primary

Measure	Time frame
Main Objective: To compare the results of frozen.thawed embryo transfers with and without GnRH analog support;Secondary Objective: S-hCG, S-Prog S-E2 The lenght of the luteal phase Bleeding in luteal phase;Primary end point(s): Pregnancy rate, implantation rate, miscarriages, live birth rate, multiple birth rate;Timepoint(s) of evaluation of this end point: One year after the last embryo transfer	—

Secondary

Measure	Time frame
Secondary end point(s): S-hCG, S-Prog S-E2 The lenght of the luteal phase Bleeding in luteal phase;Timepoint(s) of evaluation of this end point: Within a year from the last embryo transfer	—

Countries

Finland

Contacts

Public ContactVarpu Jokimaa

Turku University Hospital

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026