Effect of cancer treatment on vascular function in patients with testicular cancer

Effect of chemotherapy on endothelial function in patients with testicular cancer

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2012-004450-28-FI

Enrollment

Registered

2013-01-07

Start date

2013-02-18

Completion date

Unknown

Last updated

2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Testicular cancer MedDRA version: 14.1 Level: LLT Classification code 10043362 Term: Testis neoplasm malignant System Organ Class: 100000004864 MedDRA version: 14.1 Level: LLT Classification code 10043321 Term: Testicular germ cell cancer NOS System Organ Class: 100000004864

Interventions

Trade Name: Cisplatin Pharmaceutical Form: Concentrate and solvent for solution for infusion Other descriptive name: CISPLATIN Trade Name: Bleomycin Baxter Product Name: Bleomycin Pharmaceutical Form

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Newly diagnosed testicular cancer Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 80 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: No exclusion criteria

Design outcomes

Primary

Measure	Time frame
Main Objective: To study possible adverse effects of chemotherapy on endothelial function;Secondary Objective: Mechanisms of endothelial injury;Primary end point(s): Endothelial injury;Timepoint(s) of evaluation of this end point: Pre-treatment, immediately after second chemotherapy cycle and one year after completion of treatment	—

Secondary

Measure	Time frame
Secondary end point(s): None;Timepoint(s) of evaluation of this end point: None	—

Countries

Finland

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026