Severe acute respiratory failure
Conditions
Interventions
Trade Name: Oxígeno medicinal líquido carburos metálicos, gas para inhalación 99,5% en tanques.
Product Name: Oxígeno medicinal
Product Code: 66969
Pharmaceutical Form: Inhalation gas
Current Sponsor
Sponsors
Fundación para la Investigación Biomédica
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?Patients of both major sexes of 18 years joined UCI. ?severe acute respiratory failure defined clinical for: peripheral Saturation of oxygen (SatO2p by means of pulsioximetria) =65 years) yes F.1.3.1 Number of subjects for this age range 95
Exclusion criteria
Exclusion criteria: ?Glasgow <11 ? Need of urgent intubation ?sharp Agitation without collaboration of the patient ? Shock with instability hemodinámica that does not answer to volume and aminas vasoactivas. ? Any patient who to criterion of the investigator could not expire with the specifications of the protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: 1. To Evaluate if the high flow oxigen therapy with warm system of humidificación by means of nasal glasses (optiflow) opposite to the conventional oxygen therapy like treatment of the severe acute respiratory failure of any etiology determines a minor need of intubation orotraqueal. 2. To evaluate if the system optiflow provides a better tolerance and comfort of the patient with severe acute respiratory failure that needs oxygen therapy to high concentrations of oxygen.;Secondary Objective: To evaluate if there exist variables of the clinical initial situation and of the clinical evolution and / or gasométrica of the first 24 hours after the recruitment, which they could endure as predictive factors of intubation orotraqueal in these patients.;Primary end point(s): 1.Need of intubation orotraqueal 2. Tolerance and comfort on the utilization of the devices of oxygen therapy.;Timepoint(s) of evaluation of this end point: Need of intubation orotraqueal (hours up to the intubation, days of intubation),Parameters: ' Respiratory (respiratory frequency, SatO2p), ' Gasométricos (pH, pO2, pCO2 and balance acid - base) Tolerance and comfort on the utilization of the devices of oxygen therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): Exitus, Infection nosocomial, Pneumonia, days of stay in UCI and in the hospital;Timepoint(s) of evaluation of this end point: exitus, Infection nosocomial, Pneumonia, days of stay in UCI and in the hospital | — |
Countries
Spain
Contacts
Public ContactDpto.EECC, Rafael Fernandez
Fundación para la Investigación Biomédica
Outcome results
None listed