Influence of dexamethasone on postoperative analgesia after combined spinal epidural for cesarean delivery.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2012-001349-41-BE

Enrollment

150

Registered

2013-02-19

Start date

2012-05-15

Completion date

Unknown

Last updated

2024-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Trade Name: Aacidexam Product Name: Aacidexam Pharmaceutical Form: Concentrate for solution for injection/infusion INN or Proposed INN: Dexametasone CAS Number: 50-02-2 Other descriptive name: DEXAMET

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age>18 Elective cesarean section Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 150 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: age<18 years, preterm gestation (<37w), multiple gestations, contraindications for neuraxial anesthesia, intolerance to any of the study drugs, chronic steroid use, chronic opioid use and diabetes.

Design outcomes

Primary

Measure	Time frame
Main Objective: Is the administration of epidural or intravenous dexamethasone beneficial for postoperative analgesia after cesarean section.;Secondary Objective: Is the administration of epidural or intravenous dexamethasone benificial in the development of postoperative nausea and vomiting after cesarean section. Does the administration of epidural or intravenous dexamethasone prevents the development of chronic pain after cesarean section. ;Primary end point(s): Postoperative Analgesic need;Timepoint(s) of evaluation of this end point: 48 hours	—

Measure

Time frame

Main Objective: Is the administration of epidural or intravenous dexamethasone beneficial for postoperative analgesia after cesarean section.;Secondary Objective: Is the administration of epidural or intravenous dexamethasone benificial in the development of postoperative nausea and vomiting after cesarean section. Does the administration of epidural or intravenous dexamethasone prevents the development of chronic pain after cesarean section. ;Primary end point(s): Postoperative Analgesic need;Timepoint(s) of evaluation of this end point: 48 hours

—

Secondary

Measure	Time frame
Secondary end point(s): Pain scores (Visual analogue score) Postoperative nausea and vomiting score Development of chronic pain;Timepoint(s) of evaluation of this end point: 48 hours (pain scores/nausea and vomiting) 6months/ 1 year (develoment of chronic pain)	—

Countries

Belgium

Contacts

Public ContactDpt of Anesthesia

AZ Groeninge

matthias.Desmet@azgroeninge.be0032566330350

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026