Local infiltration analgesia a multimodal pain management strategy in total hip arthroplasty. The Anterior Supine Intermuscular technique for THA procedures will allow the patient to mobilize much earlier postoperatively, however it has been hypothesized that it will give more pain direct postoperative. This study will investigate the effect of LIA in combination with the ASI technique.
Conditions
Interventions
Trade Name: Ropivacaine HCl Fresenius Kabi
Product Name: Ropivacaine
Product Code: N01BB09
Pharmaceutical Form: Concentrate and solvent for solution for injection
INN or Proposed INN: Ropivacain HCl
C
Sponsors
Reinier de Graaf Groep
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: • Patients aged 18 years and older. • Patients willing to participate. • ASA I and II. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 20 F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range 70
Exclusion criteria
Exclusion criteria: • Patients unwilling to participate. • Mentally retarded. • Neurological conditions potentially influence pain perception. • Psychiatric conditions potentially influence pain perception. • ASA III, IV and V. • Cardiovascular impairment in the past. • Abuse of alcohol or drugs. • Known allergy for any element of the medication that is given. • Medical contra indication for spinal anaesthesia. • BMI > 40. • Rheumatoid arthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Determining the outcome of reversed and antegrade LIA in THA with ASI by analysing postoperative pain with the 100 mm Visual Analogue Scale (VAS), length of hospital stay, the amount of postoperative consumption of opioid pain medication as well as the consumption of other pain medication;Secondary Objective: not applicable;Primary end point(s): - Pain score (VAS) at day 1 at multiple moments: 1, 4 and 8 hours after operation in rest, and while and direct after mobilization starting at 4-6 hours after operation. At day 2 until the day of discharge at two moments. - Cumulative consumption of opioid medication and pain medication. - Length of Hospital Stay by amount of nights and number of hours between operation and discharge. ;Timepoint(s) of evaluation of this end point: - VAS: 1,4,8 hours after operation in rest and direct after mobilization at 4-6 hours after operation. At day 2 until discharge at 2 standardized moments: morning and afternoon. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end point(s): not applicable | — |
Countries
Netherlands
Contacts
Public ContactDepartment of orthopaedics
Reinier de Graaf Groep
Outcome results
None listed