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Impact of the clomiphene citrate intake on blood test and endometrium of women undergoing an in vitro fertilization treatment.

Impact of clomiphene citrate administration during the early luteal phase on endocrine profile in agonist triggered GnRH antagonist in vitro fertilization cycles - CLOFA

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
EU CTR
Registry ID
EUCTR2011-002173-33-ES
Enrollment
Unknown
Registered
2012-03-06
Start date
2012-05-08
Completion date
Unknown
Last updated
2012-05-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility MedDRA version: 14.1 Level: LLT Classification code 10016398 Term: Female infertility System Organ Class: 10038604 - Reproductive system and breast disorders

Interventions

Trade Name: OMIFIN comprimidos Pharmaceutical Form: Tablet INN or Proposed INN: CLOMIFENO CITRATO CAS Number: 50-41-9 Other descriptive name: CLOMIFENE CITRATE Concentration unit: mg milligram(s) Conc

Sponsors

Fundació Privada EUGIN
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Oocyte donors - Age between 18 and 35 years. - BMI between 18 and 29 kg/m2 - Presence of both ovaries - Caucasian phenotype - Basal level of E2 =65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: - Polycystic ovarian syndrome - Previous participation in the study

Design outcomes

Primary

MeasureTime frame
Main Objective: To evaluate the effect of the 5-day CC administration during luteal phase on serum LH levels in oocyte donors.;Secondary Objective: To evaluate the impact of the CC administration on the development of the endometrium.;Primary end point(s): - Serum LH levels measured in the luteal phase;Timepoint(s) of evaluation of this end point: - 1st: Basal levels. (FSH, E2, and P4 required for inclusion). - 2nd: On the ovulation triggering day. - 3rd: On day 1 after OPU. - 4th: On day 5 after OPU. - 5th: On day 7 after OPU. - 6th: On day 10 after OPU. - 7th: On the first day of next period.—

Secondary

MeasureTime frame
Secondary end point(s): - Endometrial development on day 5 after Oocyte Pick-Up (OPU) studied by histological dating criteria of Noyes;Timepoint(s) of evaluation of this end point: - day 5 after OPU—

Countries

Spain

Contacts

Public ContactClinical Research Information

Fundació Privada EUGIN

dgarcia@eugin.es00349332211227344

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026