Healthy volunteer who will have a surgery requiring curare administration (amygdalectomy...) MedDRA version: 12.1 Level: LLT Classification code 10042609 Term: Surgery MedDRA version: 12.1 Level: LLT Classification code 10057290 Term: Curarization
Conditions
Interventions
Trade Name: Atracrurium HOSPIRA
Pharmaceutical Form: Intravenous infusion
INN or Proposed INN: ATRACURIUM BESILATE
CAS Number: 64228815
Concentration unit: mg/kg milligram(s)/kilogram
Concentration ty
Sponsors
CHU de Saint-Etienne
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Parents (or holders of the parental authority) having signed the form of consent - Children from 4 to 15 years old and 3 months and seen in consultation of anesthesia for a surgical operation requiring a general anesthesia with curarization - Normal ophtalmological assessment Are the trial subjects under 18? yes Number of subjects for this age range: F.1.2 Adults (18-64 years) no F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: - Presence of a previous ophtalmological history - Children whose behavior lets augur of an inferior cooperation during the taking of photos - Children presenting an abnormality of the limb
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Measure the effect of the deep general anesthesia with curarisation on the total horizontal deviation of the eyes of non-strabismus children;Secondary Objective: - Measure the total horizontal deviation of eyes under deep general anesthesia, before the injection of the curare - Measure the horizontal deviation, the eye by eye under deep curarisée general anesthesia ;Primary end point(s): The total horizontal deviation of 2 eyes under deep AG (determined by the BIS < 50) curarized (determined by TOF=0/4) compared with the position of globes in the waking state | — |
Countries
France
Outcome results
None listed