EFFECTS OF BETA 2 RECEPTOR BLOCKADE ON PULMONARY FUNCTION IN A HUMAN MODEL OF ACUTE HYDRIC OVERLOAD

EFFECTS OF BETA 2 RECEPTOR BLOCKADE ON PULMONARY FUNCTION IN A HUMAN MODEL OF ACUTE HYDRIC OVERLOAD -

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2010-020357-14-IT

Enrollment

Registered

2012-03-06

Start date

2011-05-16

Completion date

Unknown

Last updated

2012-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

BETA BLOCKADE AND LUNG FUNCTION

Interventions

Trade Name: CONGESCOR*100CPR RIV 2,5MG Pharmaceutical Form: Coated tablet INN or Proposed INN: BISOPROLOL FUMARATE CAS Number: 66722-45-0 Concentration unit: mg milligram(s) Concentration type: equal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy subjects aging between 30 and 60 yearsl Are the trial subjects under 18? no Number of subjects for this age range: 0 F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range 20 F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: pregnancy, or breast feeding, CoPD

Design outcomes

Primary

Measure	Time frame
Main Objective: to avaluate the effects of beta 2 receptor blockade on pulmonary function in healthy subjects after water load;Secondary Objective: none;Primary end point(s): absolute or percentage variations of DLCO;Timepoint(s) of evaluation of this end point: before and after 7 days of treatment	—

Secondary

Measure	Time frame
Secondary end point(s): none;Timepoint(s) of evaluation of this end point: -	—

Countries

Italy

Contacts

Public ContactReferente OsSC

Centro Cardiologico Monzino

atanasio.nonis@ieo.it02-57489848

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026