We will try to prevent preeclampsia, groth restriction and prematurity by vitamin D supplementation given as one dose in mid pregnancy MedDRA version: 12.1 Level: LLT Classification code 10036485 Term: Pre-eclampsia MedDRA version: 12.1 Level: LLT Classification code 10036590 Term: Premature baby MedDRA version: 12.1 Level: LLT Classification code 10053759 Term: Growth retardation
Conditions
Interventions
Trade Name: Vitamin D Forte
Product Name: Cholekalciferol
Product Code: A11CC01
Pharmaceutical Form: Oral drops*
INN or Proposed INN: Cholekalciferol
CAS Number: 50-14-6
Current Sponsor code: A11cc01
Sponsors
Karolinska University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All pregnat women from 3 maternal health care units who accept to enter, alltogether 1000 Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) no F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: <18 years of age Hyperparathoroidism Sarcoidosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Lower the incidence of placental related pregnancy complications (preeclampsia, growth restriction, and prematurity);Secondary Objective: Differences in blood flow in umbilical artery, blood loss at delivery, preeclampsia, growth restriction, or prematurity;Primary end point(s): See primary and secondary outcome | — |
Countries
Sweden
Outcome results
None listed