Postoperative Analgesia in patients undergoing operative repair of fractured neck of femur
Conditions
Interventions
Trade Name: 0.5% Chirocaine
Product Name: LEVOBUPIVACAINE
Pharmaceutical Form: Solution for injection
Sponsors
Belfast Health & Social Care Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for subjects i) ASA class I-III (American Society Of Anesthesiologists Grading) ii) Patients able to give written informed consent iii) Patients requiring operative repair of fractured neck of femur Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Exclusion criteria i) History of allergy to any of the medications used in the study ii) Patients with a history of dementia or difficulty in providing informed consent iii) Patients with a history of significant neurological impairment of one or both of the lower limbs iv) Patients with a pathological fracture of the neck of femur v) Patients suffering from severe hypotension such as cardiogenic or hypovolaemic shock or with a serious cardiac arrhythmia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Comparison of postoperative pain scores after one of two nerve blocks using one of two doses of the local anaesthetic following operative repair of fractured neck of femur. ;Secondary Objective: Secondary end points (i) Incidence of motor blockade (ii) Postoperative analgesia requirements and time to first request of postoperative analgesia (iii) Ability to mobilise on the first postoperative day (iv) Incidence of any adverse events ;Primary end point(s): Comparison of postoperative pain scores after one of two nerve blocks using one of two doses of the local anaesthetic following operative repair of fractured neck of femur. | — |
Countries
United Kingdom
Outcome results
None listed