Duodenal and gastric ulcer recurrence with Helicobacter P. infection MedDRA version: 9.1 Level: LLT Classification code 10065231 MedDRA version: 9.1 Level: LLT Classification code 10051790
Conditions
Sponsors
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: both genders, age > 18 years, persistent infection from Helicobacter pylori, at gastroscopy or 13C urea breath test, after 5 eradication therapies. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Verified allergies to the acetylcysteine or to the antibiotics to cure Helicobacter pylori, pregnancy, nursing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Effectiveness of acetylcysteine in ?rescue? therapy for Helicobacter pylori infection. Due to lytic action on the gastric mucus, the administration of acetylcysteine in the 7 preceding days the antibiotic therapy, after endoscopy with culture and consequent antibiotic susceptibility testing, would allow a best aggression of the Helicobacter from selected antibiotics.;Secondary Objective: ND;Primary end point(s): Helicobacter pylori eradication | — |
Countries
Italy
Outcome results
None listed