Stroke MedDRA version: 9.1 Level: LLT Classification code 10055221 Term: Ischemic stroke
Conditions
Interventions
Trade Name: TORVAST
Pharmaceutical Form: Tablet
INN or Proposed INN: Atorvastatin
Concentration unit: mg milligram(s)
Concentration type: equal
Concentration number: 20-
Sponsors
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age ranging from 18 and 90 years; -Ischemic cerebral stroke with a neurologic syndrome related to a partial or complete infarct of posterior and/or anterior cerebral vascularization territory, following Bamford criteria. Included patients have to present one of the following clinical presentations: 1. at least one fo the following neurological deficits (depending to just one hemisphere impairment): 1.a. dysphasia or dyscalculia (for the impairment of the dominant hemisphere), visuo-spatial defict (i.e. neglect) for the impairment of the non-dominant hemisphere; 1.b. motor or sensory deficit involving at least two somatic districts, including face, arm and leg in the same side. 1.c. Homonymous hemianopsia or quadrantanopsia. 2. isolated superior function cerebral deficit. 3. motor or sensory deficit involving one arm or the face and the hand of the affected side. 4. vertebro-basilar syndrome. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: hemorrhagic stroke -Neurological deficit due to other causes instead of ischemia. -participation in another research protocol. -Blood, autoimmune or inflammatory cerebral diseases. -impossibility to partecipate to follow-up clinical controls.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Effects of the atorvastatine in the prognosis and in the frequency of new strokes during the follow-up period.;Secondary Objective: ND;Primary end point(s): ND | — |
Countries
Italy
Outcome results
None listed