Patients with Atopic Dermatitis, Ichtyosis vulgaris and X-linked Ichtyosis
Conditions
Interventions
Trade Name: Canoderm
Product Name: Canoderm
Pharmaceutical Form: Cream
INN or Proposed INN: urea
Concentration unit: mg/g milligram(s)/gram
Concentration type: equal
Concentration number: 50-
Trade N
Sponsors
Department of Medical Sciences, Dermatology and venerology, Uppsala University, Uppsala Sweden
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with atopic dermatitis, ichtyosis vulgaris and x-linked ichtyosis. 18-65 yrs of age Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Any other concomittant skin disease. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To achieve better knowledge about the cause of the impaired skinbarrier function in patients with atopic dermatitis, ichtyosis vulgaris and x-linked ichtyosis. ;Secondary Objective: To achieve more knowledge about the effects of emollients on this impaired barrier function, and about which ingredients in emollients that have beneficial or maybe negative effects on the barrier function in these patients. To study if the effects of the different emollients are correlated to the different genotypes in the filaggring gene and a gene coding for steroid sulphatase. ;Primary end point(s): To evaluate the effect of 4 weeks daily treatment with emollients on the skin barrier function in patients with impaired barrierfunction. + see E.2.1 | — |
Countries
Sweden
Outcome results
None listed