A Comparison of Remifentanil Patient-Controlled Analgesia vs. Oral Morphine Analgesia for Dressing Changes in Burns Patients.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2008-007322-19-GB

Enrollment

Registered

2010-11-23

Start date

2009-07-07

Completion date

Unknown

Last updated

2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain experienced by patients with pre-existing burns presenting to the burns outpatients unit requiring two or more dressing changes

Interventions

Trade Name: Remifentanil Product Name: Remifentanil Pharmaceutical Form: Powder for solution for infusion Trade Name: Oramorph Product Name: Oramorph Pharmaceutical Form: Oral solution

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Outpatients requiring two or more dressing changes for burns who would normally be considered appropriate for oral morphine analgesia. • ASA 1 and 2 patients over the age of 18 years Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: • Patients unable to use the hand control of the PCA device • Patients who are unable to give full consent or do not agree to participate in the trial • Hypersensitivity or history of serious adverse reactions to remifentanil or morphine • Surgical or anaesthetic objections • Pregnancy

Design outcomes

Primary

Measure	Time frame
Main Objective: To determine whether remifentanil PCA or oral morphine provides more effective analgesia for out-patient dressing changes in the burns unit. ;Secondary Objective: To determine if burns patients prefer traditional analgesia or remifentanil analgesia for dressing changes ;Primary end point(s): Maximum visual analogue scale (VAS) pain score during the dressing change procedure.	—

Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026