patients with coronary arteries desease, who need Tc multislice for diagnostic reasons MedDRA version: 9.1 Level: SOC Classification code 10007541
Conditions
Interventions
Pharmaceutical Form: Tablet
INN or Proposed INN: Ivabradine
Concentration unit: mg milligram(s)
Concentration type: equal
Concentration number: 5-
Pharmaceutical Form: Tablet
INN or Proposed INN: Met
Sponsors
AZIENDA OSPEDALIERA DI PARMA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)age>18 years 2)sinusal rithm 3)heart rate>65bpm 5)signed informed consent Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: 1) age 90/50) 6) Arrythmias disease 7) Hearth failure ( NYHA III- IV) 8) Severe epatic failure 9) Unstable angina 10) Pregnancy 11) Concomitant drugs metabolized from Cit P450 3A 12) Antiarrythmic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The aim of the study is to value the feasability and the security of ivabradine used in the reduction of hearth rate before multislice TC.;Secondary Objective: - Comparison in the effectiveness of reduction of hearth rate between Ivabradine and methoprolol ; - Comparison in the performance to value segments of coronary arteries and in the imaging quality of Ivabradine and Metoprolol.;Primary end point(s): Hearth rate value before multislice TC in patient treated with ivabradine and with metoprololo. Comparison with the initial value. The number of coronary arteries segments scanned in patient treated with ivabradine and metoprolol and the imaging quality. | — |
Countries
Italy
Outcome results
None listed