Pacientes con pterigión primario no intervenido. Patients suffering from untreated primary pterygium.
Conditions
Sponsors
Center for Biomedical Research of La Rioja (CIBIR)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients suffering from pterygium. Must be 18 years old or older. Able to comply with treatment and follow-up visit. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Patients younger than 18. Pregnant women, lactating mothers, and women trying to get pregnant. Allergies to tetracyclines. Patients taking drugs incompatible with tetracyclines. Serious cardiac or cerebrovascular disease during 6 months previous to the study. Patients that cannot be regularly followed because of psycological, social, familiar, or geographical reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Secondary Objective: We will also study whether doxycycline treatment reduces the number of secondary growths following resection of pterygium. A genomic/proteomic study will be performed on the tissue specimens obtained from chirurgical resection of pterygium.;Main Objective: The main objective of the study is to reduce pterygium growth using a pharmacological treatment and reduce the number of pterygium patients that need to be subjected to surgery.;Primary end point(s): Photographs of the eye affected by pterygium will be taken during the first visit and at the second visit following 4 weeks of treatment. The area covered by pterygium will be quantified. The quotient between the surface in the second visit and the area of the first visit will provide a growth or diminution ratio. This ratio will be the primary end point of the study. | — |
Countries
Spain
Outcome results
None listed