Investigation of the use a Fascia Iliaca nerve blockade for both positioning for spinal anaesthesia and postoperative analgesia in patients undergoing operative repair of fractured neck of femur.
Conditions
Interventions
Trade Name: CHIROCAINE (0.25%)
Pharmaceutical Form: Solution for injection
Trade Name: LIDOCAINE 1%
Pharmaceutical Form: Solution for injection
Trade Name: HYPNOVEL
Product Name: MIDAZOLAM
Pharmaceu
Sponsors
BELFAST HEALTH & SOCIAL CARE TRUST
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: i) ASA class I-IV ii) Patient able to give written informed consent iii) Patients requiring operative repair of fractured neck of femur Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: i) History of dementia or difficulty in obtaining consent ii) History of allergy to any of the medications used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The main objectives of the trial are firstly to evaluate the reduction in visual analogue scores (VAS) during positioning for spinal anaesthesia following the administration of either a fascia iliaca compartment block or a combination of iv midazolam and ketamine in patients undergoing operative repair of fractured neck of femur and secondly to evaluate the reduction in visual analogue scores (VAS) for pain at rest and with hip flexion after administration of either a single shot or bolus top-up compartment block in the postoperative period. ;Secondary Objective: 1. To assess the length of time to first request of additional analgesia 2. To evaluate the level of assistance required for transfer from the sitting to the standing position 3. To document the incidence and severity of motor blockade 4. To document the time taken to mobilisation with walking aid 5. Measurement of oxygen saturations without supplemental oxygen in both groups 6. To evaluate the incidence of all complications associated with the analgesic techniques in both groups. 7. To assess the incidence of nausea and/or vomiting within the first 48 hours after surgery in both groups 8. To assess the use of blood products in all groups 9. To determine the level of patient satisfaction with both techniques ;Primary end point(s): The reduction in VAS pain scores for both positioning for spinal anaesthesia and in the postoperative period for patients with fractured neck of femur | — |
Countries
United Kingdom
Outcome results
None listed