The degree of pain reduction in test subjects using a specific jellyfish (cnidaria) sting inhibitor and repellent lotion, compared to control subjects being protected by a normal water repellent sunscreen or no sun lotion at all. The jellyfish exposed skin parts will be treated for pain relief with hot or cold therapy or a commercially available local pain relief product (xylocain) from pharmacy.
Conditions
Interventions
Trade Name: Xylocain LINIMENT 3%: 1 g inneh.: Lidocain. 30 mg
Product Name: Xylocain liniment 3 %
Product Code: 142679
Pharmaceutical Form: Cutaneous liquid
Sponsors
Biologiske Stasjon Drøbak
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy subjects over 18 years. The subjects can be of both sexes. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Subjects with a history of certain sorts of allergic reactions are being excluded to minimize any possible risk. Subjects with a history of unusual adverse reaction to insects, jellyfish, or other types of stings will be excluded. • People with atopic diseases, e.g., asthma, allergic rhinorrhea or rhinitis, hay fever, or atopic skin inflammation • Pregnancy. • People who suffer from skin diseases in the testing regions or whose inner forearms are too hairy to allow for interpretation of the test • People who have used any medical or cosmetic product on either arm for 48 hours before the start of the experiment • People who are taking antihistamines or steroids • Subjects with medical conditions which, in the opinion of the investigator, pose risks that would prohibit participating • Subjects with a history of keloid formation will be excluded from the Jellyfish protocol • Subjects with allergy to lidocain or other local pain substances
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The purpose of the study is to investigate the effectiveness of a sun lotion containing a specific Jellyfish sting inhibitor versus regular sun lotions as controls. ;Secondary Objective: Investigate the effectiveness of hot/cold immersion for the treatment of Jellyfish (Cyanea sp) stings versus local pain relief with prescription free pharmaceutical drugs.;Primary end point(s): The primary outcome is a clinically important reduction in pain as measured by the visual analogue scale (VAS). Secondary outcomes is to count the number of nematocyst fired when use of protection versus no protection. | — |
Countries
Norway
Outcome results
None listed