Pain post wisdom tooth extraction
Conditions
Interventions
Trade Name: Perfalgan
Product Name: Perfalgan
Pharmaceutical Form: Intravenous infusion
INN or Proposed INN: N-(4-hydroxyphenyl)acetamide
CAS Number: 103-90-2
Pharmaceutical form of the placebo: Intra
Sponsors
Queen Victoria Hospital NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients over 18 having a general anaesthetic for wisdom teeth extractions – at least one of them being a lower tooth. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: o Patients who are unable to give full consent, or who do not wish to take part in the trial o Hypersensitivity or history of serious adverse reactions to paracetamol or Non-Steroidal Anti Inflammatory drugs o Active liver disease o Renal Dysfunction o Pregnant or breast feeding women o Alcohol or drug abuse o History of unresponsiveness to paracetamol o Gastric or Peptic ulcer disease o Inflammatory bowel disease o Blood coagulation abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: Does paracetamol given as a tablet give better pain relief than paracetamol given intravenously in patients having wisdom teeth removed?;Secondary Objective: None;Primary end point(s): We will compare the pain scores of patients in the two study arms one hour postoperatively. This will be done in recovery using a visual analogue scale (VAS) pain scoring system. | — |
Countries
United Kingdom
Outcome results
None listed