This study aims to investigate the possibility to obtain higher functional contrast and better spatial assessment in contrast enhanced functional Magnetic Resonance Imaging (fMRI) as compared to standard fMRI methods without contrast. There are several indications for fMRI, e.g. neurosurgical planning, diagnosis of neurological diseases, prognosis in patients with lesions, rehabilitation. MedDRA version: 9.1 Level: LLT Classification code 10029820 Term: Nuclear magnetic resonance imaging gadoli
Conditions
Interventions
Trade Name: Vasovist
Product Name: Vasovist
Pharmaceutical Form: Injection*
Sponsors
CMIV
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: healthy subjects (equal proportion of males and females) Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: left-handed subjects subjects with contraindication for MR-safety subjects with neurological and psychiatric diseases, including alcohol and drug abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: This study aims to investigate the possibility to obtain higher functional contrast in contrast enhanced functional Magnetic Resonance Imaging (fMRI) as compared to standard fMRI methods without contrast. ;Secondary Objective: This study aims to investigate the possibility to obtain better spatial assessment in contrast enhanced fMRI as compared to standard fMRI methods without contrast. ;Primary end point(s): Optimised MRI sequence with functional contrast Assessment of applicability of contrast enhanced fMRI. | — |
Countries
Sweden
Outcome results
None listed