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Een verbetering van de analgesie na episiotomie door epidurale toediening van neostigmine en clonidine.

Een verbetering van de analgesie na episiotomie door epidurale toediening van neostigmine en clonidine.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
EU CTR
Registry ID
EUCTR2007-005512-12-BE
Enrollment
Unknown
Registered
2007-11-23
Start date
2007-12-19
Completion date
Unknown
Last updated
2012-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Combinedn spinal-epidural analgesia during labour.

Interventions

Trade Name: Prostigmine Pharmaceutical Form: Injection* Other descriptive name: NEOSTIGMINE METHYLSULFATE Concentration unit: mg/ml milligram(s)/millilitre Concentration type: equal Concentration numb

Sponsors

University Hospitals Leuven
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA I or II nullipare singleton pregnancy > 37 weeks gestational stage Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: ASA III or IV no episiotomy allergy to local anesthetics

Design outcomes

Primary

MeasureTime frame
Main Objective: Does the epidural administration of clonidine and neostigmine improves analgesia after episiotomy.;Secondary Objective: What is de incidence of advers events such as: nausea, vomiting, post dural punciton headache, pruritus, sedation, maternal hypotension and bradycardia.;Primary end point(s): Does the epidural administration of neostigmine and clonidine improves analgesia after episiotomy. Does the patient need less NSAID's and paracetamol after epidurale administration of neostigmine and clonidine.

Countries

Belgium

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026