chronic heart failure MedDRA version: 6.1 Level: PT Classification code 10007558
Conditions
Interventions
Trade Name: DIAMOX
Pharmaceutical Form: Solution for injection
INN or Proposed INN: Acetazolamide
Concentration unit: mg milligram(s)
Concentration type: equal
Concentration number: 500-
Trade Name:
Sponsors
FONDAZIONE MONZINO CENTRO CARDIOLOGICO
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Male or female in-patients, age 18-80 years,with chronic heart failure, in stable clinical conditions, with periodic breath induced by exercise documented during a cardiopulmonary exercise test. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Pregnancy, lactation, important concomitant diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: to evaluate the role of CO2 and of the chemoreceptors in the genesis of periodic breath through CO2 inhalation and acute or chronic administration of acetazolamide.;Secondary Objective: na;Primary end point(s): effect on periodic breath during exercise after inhalation of C02 variation of the number of cycles of periodic breathing during chronic treatment with acetazolamide | — |
Countries
Italy
Outcome results
None listed