chronic heart failure MedDRA version: 6.1 Level: PT Classification code 10007558
Conditions
Interventions
Trade Name: DILATREND*30CPR DIV 25MG
Pharmaceutical Form: Tablet
INN or Proposed INN: Carvedilol
Concentration unit: mg milligram(s)
Concentration type: equal
Concentration number: 25-
Trade Name: CO
Sponsors
FONDAZIONE MONZINO CENTRO CARDIOLOGICO
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients of both sexes, aged between 18 and 80 years; - primitive or hyschemic dilatative cardiomiopathy, clinically stable - NYHA II or III class Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: less than 18 or more than 80 years of age; - pregnancy or lactation - important concomitant diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: to compare the effect of chronic treatment of heart failure with carvedilol, bisoprolol and nebivolol on heart-lung function assessed through exercise capacity, tolerance to hypoxia, lung function and ventilatory response of chemoreceptors.;Secondary Objective: none;Primary end point(s): 1) modifications of DLco 2) modifications of the central ventilatory response ot hypercapnia 3) responce to exercise hypoxia | — |
Countries
Italy
Outcome results
None listed