Colonization with methicillin-resistant Staphylococcus aureus (MRSA)
Conditions
Interventions
Trade Name: Novabac antibacterial skin wash
Product Name: Novabac antibacterial skin wash
Pharmaceutical Form: Cutaneous liquid
Pharmaceutical form of t
Sponsors
Belfast Health & Social Care Trust
South Eastern Health & Social Care Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients admitted to the Regional Intensive Care Unit at the Belfast Health & Social Care Trust (Royal Victoria Hospital, Belfast) and the Intensive Care Unit at the South Eastern Health & social Care Trust (Ulster Hospital, Dundonald) during the study period will be eligible for inclusion in the study Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: 1. Age < 18 years. 2. Those patients who are known to be colonized at the time of admission. 3. Patients who on admission are unlikely to remain in the ICU for at least 48 hours. 4. Patients who are recruited, whose pre-intervention MRSA screening tests are subsequently found to be positive will be withdrawn from the study. 5. Consent declined. 6. Known sensitivity to TTO.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The hypothesis of the study is that treatment with tea tree oil (Novabac) can prevent colonisation with MRSA in critically ill adults. The primary outcome is the incidence of new MRSA colonization. ; Secondary Objective: The secondary objectives are to 1) investigate if treatment with tea tree oil is more cost-effective than standard body wash (Johnston’s softwash). 2) investigate if the is no difference in sensitivity and specificity between a PCR-based assay for detection of colonization with MRSA and the standard culture method. ;Primary end point(s): The primary outcome measure will be MRSA colonization at ICU discharge, measured using standard culture techniques | — |
Countries
United Kingdom
Outcome results
None listed