Patients enrolled will have a diagnosis of restrictive lung disease diagnosed by a High Resolution CT scan, reduced gas transfer result (obtained from pulmonary function tests) and low lung volumes (obtained from pulmonary function tests). MedDRA version: 9.1 Level: LLT Classification code 10033318 Term: Oxygen saturation decreased MedDRA version: 9.1 Level: LLT Classification code 10050322 Term: Oxygen supplementation
Conditions
Interventions
Trade Name: Medical Oxygen
Product Name: BOC Oxygen Cylinder PD 300Lts 99.5%
Product Code: 0735/5000
Pharmaceutical Form: Inhalation gas
Sponsors
North Bristol NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients must have a CT confirmed diagnosis of restrictive lung disease as this is the current standard for diagnosing these disorders. - Patients must have an abnormal gas transfer PFT as this is confirmation of the extent of damage to the patients lungs. - Patients must be mobile as this is neccessary to complete a 6 minute walk test. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: - Patients who are not mobile, as they need to complete a six minute walk test. - Patients with poor comprehension, as they will not understand the instructions. - Patients who would be unable to carry or push around an oxygen cylinder. - Patients who are already prescribed long term oxygen therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: The aim is to examine if patients walking distance change, measured by a 6 minute walk test, and/or perceive their symptoms to change, measured using a quality of life questionnaire after an 8 week course of ambulatory oxygen compared to a group of patients with the same disease that don't receive oxygen.;Secondary Objective: Quality of life measurements associated with this treatment measured using the validated SF-36 quality of life questionnaire.;Primary end point(s): The aim of this study is to investigate the benefit of an 8 week course of ambulatory oxygen on patients with DPLD, both physiologically, measured using a 6 minute walk test, and psychologically, using a quality of life score. Any change in the distance walked during the 6 minute walk test both pre and post oxygen trial, and any change in teh quality of life score will be examined. | — |
Countries
United Kingdom
Outcome results
None listed