Thrombocytopenia complicating preeclampsia MedDRA version: 9.1 Level: LLT Classification code 10043554 Term: Thrombocytopenia
Conditions
Interventions
Trade Name: METHYL PREDNISOLONE
Product Name: METHYLPREDNISOLONE MERCK 20 MG
Pharmaceutical Form: Powder for injection*
Pharmaceutical form of the placebo: Solution for injection
Route of administrat
Sponsors
CHU DE POITIERS
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All pregnancies complicated by preeclampsia (defined according to ISHP criteria) with a fall of platelets =65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Women with maternal or foetal complications imposing an immediate parturition· Women with a platelet number 38°C at 2 occasions separated by 3h)· Women with diabetes, hypokalemia, or treated by medicines exposing to cardiac arrhythmia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To demonstrate efficiency of early treatment with methylprednisolone in order to reduce the fall of platelets during preeclampsia complicated of thrombocytopenia;Secondary Objective: - To assess the possibility of performing a regional anesthesia for delivery - To evaluate maternal and foetal tolerance of methylprednisolone;Primary end point(s): platelet count > 50 x 109/L at H36 | — |
Countries
France
Outcome results
None listed