Neovascular Glaucoma MedDRA version: 8.1 Level: LLT Classification code 10062891 Term: Neovascular glaucoma
Conditions
Sponsors
Moorfields Eye Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 21 years or older Willingness to comply Signed informed consent Diagnosis of neovascular glaucoma in at least one eye Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Any patient uncooperativeness that restricts adequate examination of the eye Any concurrent infectious/noninfectious conjunctivitis or keratitis in either eye Any history of allergic hypersensitivity or poor tolerance to any components of the preparations used in this trial Females of childbearing potential not using reliable means of birth control Pregnant or lactating females Any clinically significant, serious, or severe medical or psychiatric condition Participation (or current participation) in any investigational drug or device trial within 30 days prior to Visit 1 Inability to understand the trial procedures, and thus inability to give informed consent Serious systemic, psychological or ocular disease Unwillingness to accept the risks associated with intravitreal injections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To assess subjective pain relief following treatment using a pain-scoring questionnaire;Secondary Objective: Intraocular pressure at each time point Regression of iris vessels Anterior chamber flare and cell count Visual acuity;Primary end point(s): a. pain score questionnaire b. measurement of visual acuity c. measurement of intraocular pressure d. photography to assess iris neovascularisation e. measurement of anterior chamber flare and cell count | — |
Countries
United Kingdom
Outcome results
None listed