A pilot study into the effect of 5-Aminolevulinic Acid Photodynamic Therapy in the management of oral Lichen Planus - Pilot study into the use of PDT for Oral Lichen Planus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-004696-35-GB

Enrollment

Registered

2007-04-17

Start date

2007-06-08

Completion date

Unknown

Last updated

2012-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Lichen Planus MedDRA version: 8.1 Level: LLT Classification code 10030983 Term: Oral lichen planus

Interventions

Trade Name: Porphin Cream Product Name: 5-Aminolevulinate Product Code: 5-Aminolevulinate Pharmaceutical Form: Cream CAS Number: 5451-09-2 Other descriptive name: 5-aminolevulinic acid hyrochloride 20

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Willingness to participate Oral lesions affecting the mouth lining Able to use cream on lesion for 15 -30mins Able to comply with instructions Women of childbearing potential who are not pregnant Age - 18-75 years Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Patients with obvious malignant disease Those potential participants who cannot give their own informed consent Pregnant women Patients who have porphyria

Design outcomes

Primary

Measure	Time frame
Main Objective: To treat Oral Lichen Planus and reduce the patients' requirement for immunosuppressant treatment.;Secondary Objective: Reduce the symtoms of Oral Lichen Planus;Primary end point(s): Reduced immunosuppressant use following treatment	—

Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026