The use of Single dose intravenous paracetamol "Perfalgan" in Early extubation cardiac surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-004389-15-GB

Enrollment

Registered

2007-02-12

Start date

2007-04-05

Completion date

Unknown

Last updated

2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extubation time following coronary artery bypass surgery

Interventions

Trade Name: Perfalgan Pharmaceutical Form: Intravenous infusion INN or Proposed INN: PARACETAMOL CAS Number: 103902 Concentration unit: mg milligram(s) Concentration type: equal Concentration number:

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Patients undergoing elective coronary artery bypass surgery patients =65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Inability to obtain informed consent Allergy to intravenous paracetamol Deranged pre operative liver function

Design outcomes

Primary

Measure	Time frame
Main Objective: Does single dose intravenous paracetamol provide clinical benefit in early extubation coronary artery bypass surgery;Secondary Objective: ;Primary end point(s): Amount of morphine used pre operatively by the patient Time to extubation Arterial carbon dioxide concentrations	—

Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026