Prophylaxis with fenoldopam in cardiac surgery patients at high risk of postoperative renal failure - ND

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-003053-24-IT

Enrollment

160

Registered

2006-12-14

Start date

2006-05-18

Completion date

Unknown

Last updated

2012-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac surgery patients at high risk of postoperative renal failure MedDRA version: 9.1 Level: HLGT Classification code 10007593 Term: Cardiac therapeutic procedures

Interventions

Trade Name: CORLOPAM*20MG/2ML IV 1F 2ML Pharmaceutical Form: Solution for infusion INN or Proposed INN: Fenoldopam CAS Number: 67227-57-0 Concentration unit: µg microgram(s) Concentration type: equal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: cardiac surgery requiring cardiopulmonary bypass in patients - high risk of postoperative renal failure - informed consent Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: -preoperative dialysis, - glaucoma, - allergy to fenoldopam

Design outcomes

Primary

Measure	Time frame
Main Objective: Efficacy of fenoldopam in postoperative renal failure prophylaxis in cardiac surgery;Secondary Objective: to decrease the incidence of postoperative oliguric renal failure and dialysis-dependent renal failure, the duration of postoperative intensive care unit and hospital stay;Primary end point(s): to decrease the incidence of postoperative renal failure, defined as an increase of baseline creatinine 50	—

Measure

Time frame

Main Objective: Efficacy of fenoldopam in postoperative renal failure prophylaxis in cardiac surgery;Secondary Objective: to decrease the incidence of postoperative oliguric renal failure and dialysis-dependent renal failure, the duration of postoperative intensive care unit and hospital stay;Primary end point(s): to decrease the incidence of postoperative renal failure, defined as an increase of baseline creatinine 50

—

Countries

Italy

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026