The use of morphine in addition to local anaesthetic for post operative analgesia in anterior cruciate reconstruction - ACL pain trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-002731-24-GB

Enrollment

Registered

2006-07-23

Start date

2006-07-12

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rupture of anterior cruciate ligament being corrected by anterior cruciate reconstruction.

Interventions

Trade Name: Morphine 10mg in 1ml injection Product Name: Morphine 10mg in 1ml injection Pharmaceutical Form: Injection* Trade Name: Marcain 0.5% Polyam

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged16-50 years with symptomatic ACL rupture coming for ACR surgery. Able to give informed consent. Are the trial subjects under 18? yes Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Patients with multiple ligament injuries; previous ACL surgery; known established osteoarthritis.

Design outcomes

Primary

Measure	Time frame
Main Objective: Can post-operative analgesia after anterior cruciate reconstruction (ACR) be improved by adding morphine to local anaesthetic instilled into to the joint at the end of the procedure?;Secondary Objective: How well do patient’s pre-operative expectations of pain experience match their actual experience after ACR surgery?;Primary end point(s): VAS scores post-operatively, compared between groups.	—

Measure

Time frame

Main Objective: Can post-operative analgesia after anterior cruciate reconstruction (ACR) be improved by adding morphine to local anaesthetic instilled into to the joint at the end of the procedure?;Secondary Objective: How well do patient’s pre-operative expectations of pain experience match their actual experience after ACR surgery?;Primary end point(s): VAS scores post-operatively, compared between groups.

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Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026