A comparison of two methodes for pastoperative paintreatment after knee replacement. Pharmacokinetics and clinical effect of femoral block and local infiltration of the operation area of ropivacaine.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-002581-19-SE

Enrollment

Registered

2006-06-08

Start date

2006-10-10

Completion date

Unknown

Last updated

2012-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee replacement Postoperative paintreatment

Interventions

Trade Name: narop Product Name: narop Pharmaceutical Form: Injection* Trade Name: Toradol Product Name: Toradol Product Code: M01A B15 Pharmaceutical Form: Injection* Trade Name: Adenalin Product Na

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult males or females ASA 1-3 undergoing spinal anesthesia for elective knee replacement. Have sign informed consent. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Allergy for NSAID or local anaesthetic. Bleeding disorders Demens or psychiatric disorder. Patints who refusesto partisipart. Av-block II or III Hepato renal disorders ulcus duodeni or ventriculi

Design outcomes

Primary

Measure	Time frame
Main Objective: Quality control of paintreatment after knee replacement. Two methodes will bee compared, Femoral block or local infiltration in the operating area during surgery. ;Secondary Objective: Plasmaconcentration of Ropivacaine and its pharmacokinetics during first 12 hours after surgery.;Primary end point(s): Vas registration for pain	—

Countries

Sweden

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026