A Randomised Study to Investigate the Effectiveness of Acupuncture for the Relief of Dyspnoea in Patients with Non-Small Cell Lung Cancer - Acupuncture for dyspnoea in non-small cell lung cancer

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-000810-18-GB

Enrollment

141

Registered

2006-03-13

Start date

2006-05-11

Completion date

Unknown

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Trade Name: Oramorph Product Name: Oramorph Product Code: Oramorph Pharmaceutical Form: Oral liquid

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Written informed consent 2. Male or female 3. Age >18 years 4. Subjective dyspnoea 5. ECOG performance status: 0-3 Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: 1. Recent acupuncture 2. Relative contraindication to acupuncture 3. Current use of morphine 4. Untreated anaemia, pleural effusion, pulmonary embolism, pneumonia, superior vena cava obstruction or ascites, if treatment appropriate 5. Pregnancy 6. Commenced steroids or changed dose within one week of start of study 7. Chemotherapy, radiotherapy or hormonotherapy in last 4 weeks

Design outcomes

Primary

Measure	Time frame
Main Objective: To investigate whether use of acupuncture in lung cancer-related breathlessness improves symptoms when compared with use of morphine; Secondary Objective: 1. To improve dyspnoea control by measuring total dose of morphine used at 24 hours 2. To improve lung function tests 3. To reduce other symptoms eg anxiety 4. To measure quality of life 5. To document patients' experience of treatment ;Primary end point(s): Comparison of effectiveness of treatments in the improvement of dyspnoea comparing the percentage of patients in each treatment arm with at least a 1.5 point change in the VAS for dyspnoea.	—

Measure

Time frame

Main Objective: To investigate whether use of acupuncture in lung cancer-related breathlessness improves symptoms when compared with use of morphine; Secondary Objective: 1. To improve dyspnoea control by measuring total dose of morphine used at 24 hours 2. To improve lung function tests 3. To reduce other symptoms eg anxiety 4. To measure quality of life 5. To document patients' experience of treatment ;Primary end point(s): Comparison of effectiveness of treatments in the improvement of dyspnoea comparing the percentage of patients in each treatment arm with at least a 1.5 point change in the VAS for dyspnoea.

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Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026