The effect of dexmedetomidine sedation on intracranial and cerebral perfusion pressures in patients with acute severe brain injury

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2006-000660-89-FI

Enrollment

Registered

2006-02-20

Start date

2006-03-23

Completion date

Unknown

Last updated

2012-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute blunt traumatic brain injury with intracranial abnormalities on the initial computed tomography (CT) scan consistent with head trauma, initial Glasgow Coma Scale (GCS) score =8 or GCS score deteriorating to =8 within 24 hrs following injury and need for ICP monitoring (determined by the responsible neurosurgeon), intubation, mechanical ventilation and continuous sedation.

Interventions

Trade Name: Precedex Pharmaceutical Form: Intravenous infusion Trade Name: Propofol -Lipuro Pharmaceutical Form: Intravenous infusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Main Objective: ;Secondary Objective: ;Primary end point(s):	—

Countries

Finland

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026