Healthy male volunteers
Conditions
Interventions
Trade Name: Synacthen Depot
Pharmaceutical Form: Solution for injection
Pharmaceutical form of the placebo: Solution for injection
Route of administration of the placebo: Intramuscular use
Sponsors
Univ. of Iceland, Dept. Pharmacol.
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Healthy, male, age 18-60 years. Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: History of endocrine-, renal-, malignant or inflammatory disease. Treatment with a drug that affects blood-lipids. Allergy for Synacthen Depot og any other drug containing ACTH. Cooperation problems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To establish the blood-lipid lowering effetcts of ACTH. To find the most appropriate dosing interval that gives a steady lipid-lovering effect.;Secondary Objective: Recording of adverse reactions.;Primary end point(s): Serum concentration of LDL-cholesterol and apolipoprotein-B. | — |
Countries
Iceland
Outcome results
None listed