Carotid endarterectomy is an operation performed on patients with a symptomatic stenosis of the internal carotid artery. Such patients have usually presented with stroke or transient ischaemic attack. The degree of stenosis is estimated by Doppler ultrasound. Patients are only operated on if there is 70-99% stenosis.
Conditions
Interventions
Trade Name: Oxygen
Product Name: oxygen
Pharmaceutical Form: Inhalation gas
Sponsors
Oxford Radcliffe Hospitals NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients undergoing carotid endarterectomy under regional anaesthesia Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Patient refusal for regional anaesthesia Patient refusal to participate in the trial Non-English speaking (this would preclude regional anaesthesia techniques anyway) Complete contralateral internal carotid artery occlusion Inability to apply bilateral sensors to patient's forehead
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To investigate whether increasing the inspired oxygen concentration improves cerebral oxygenation during the period of carotid cross-clamping in patients undergoing carotid endarterectomy (CEA) under regional anaesthesia.;Secondary Objective: ;Primary end point(s): Patient participation in the trial is concluded at the end of surgery when all readings have been obtained | — |
Countries
United Kingdom
Outcome results
None listed