Minor superficial and partial thickness burns <5% body surface area.
Conditions
Interventions
Product Name: Morphine and intrasite gel
Pharmaceutical Form: Gel
INN or Proposed INN: morphine sulphate
Concentration unit: g/ml gram(s)/millilitre
Concentration type: equal
Concentration number: 10m
Sponsors
Portsmouth Institution Medicine, Health & Social Care, Portsmouth University
Research & Development Unit, Queen Alexandra Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Over 7 years of age and deemed competent to give own informed consent. - If aged 7-15 inclusive must be accompanied by adult with parental responsibility. - Attending A&E with a minor superficial or partial thickness burn that does not require the patient to be admitted to hospital or transferred to a burns specilaist, as per the National Burn Inury Referral Guidelines. - Burn must be caused by hot water/steam, a hot surface of sunburn. - Burn must be less than 8 hours old at first attendance to A&E. Are the trial subjects under 18? yes Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) yes F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: - Minors aged 7-15 years unaccompanied by adult with parental responsibility. - Persons unable to give their own informed consent. - Burns to the head, neck, face & genitalia. - Electrical and chemical burns. - Pregnant women. - Persons with other injuries. - Persons with altered perceptions to pain due to pathophysiology of disease, alcohol or drugs. - Patients requiring a stat dose of opiod-based medication to control their pain on arrival to A&E. - Persons regularly prescribed opiod-based medications. - Persons who appear to be under the influence of alcohol or illicit drugs at time of attendance to A&E -
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To test the analgesic efficacy of morphine when applied topically to a burn.;Secondary Objective: To compare the comfort of a dressing containing morphine and intrasite gel, with an intraiste gel only or standard Jelonet dressing when applied to a burn;Primary end point(s): To obtain 4 pain score ratings and one comfort rating from 63 particpants in 6 months | — |
Countries
United Kingdom
Outcome results
None listed