Patients scheduled for toncilectomia need postoperative paintreatment. Morphine has sideeffects: Nausea, vomiting, sedation and dizziness. These sideeffects are og couse unpleasent for the patient and sometimes prolongs there stay in the hospital.
Conditions
Interventions
Product Name: pregabalin
Pharmaceutical Form: Capsule*
Pharmaceutical form of the placebo: Capsule*
Route of administration of the placebo: Oral use
Product Name: Dexometason
Pharmaceutical Form: Int
Sponsors
Dept. of Anaestesiology, University hospital in Glostrup
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - patients sheduled for a toncilectomie - age between 18 and 50 - ASA 1-2 - given informed content Are the trial subjects under 18? no Number of subjects for this age range: F.1.2 Adults (18-64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range
Exclusion criteria
Exclusion criteria: Patients who - are unable to cooperate - does not speak and understand danish - has allergy for the drugs used in the trial - drug or alkohol abuse - epilepsi - medicaly treated diabetes - know kidney disease - daily use of analgesi - daily use of antacida - pregnant or nursing - in antidepressiv treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main Objective: To improve the postoperative pain treatment on patients who have had done a toncilectomi, by using a new combination of secondary analgesics, and thereby hopefully minimizing the patients need for morphine postoperativly;Secondary Objective: To see if a known analgesic effect of fortecontin and paracetamol combined with a new drug, pregabalin can act synergistically in patients how have done a toncilectomia.;Primary end point(s): Painscore after 2,4 and 24 hours after surgery - in rest Painscore after swollowing 50 ml of water 2,4 and 24 hours after surgery | — |
Countries
Denmark
Outcome results
None listed