TOLERANCE OF MILK FEEDS IN PRETERM, VERY LOW BIRTH WEIGHT BABIES: THE USE OF GLYCERINE SUPPOSITORIES

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

EU CTR

Registry ID

EUCTR2005-000302-31-GB

Enrollment

Registered

2005-03-31

Start date

2005-04-25

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The problem is inability to sustain enteral feeding in very low birth weight babies due to feed intolerance. The necessity for parenteral feeding creates risk of sepsis, cholestasis,increased oxygen requirement and abdominal distension

Interventions

Product Name: Glycerin 250mg suppository Pharmaceutical Form: Suppository

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion and Exclusion Criteria The study group will include all preterm babies born at Wishaw General Hospital at less than 32 weeks’ gestation. Babies are stratified in two main groups based on their gestational age- a) =65 years) no F.1.3.1 Number of subjects for this age range

Exclusion criteria

Exclusion criteria: Babies will be excluded from the study if they have major dysmorphic features, are found to have a structural gastrointestinal anomaly, develop Necrotising Enterocolitis or suffer perinatal hypoxic ischaemic encephalopathy.

Design outcomes

Primary

Measure	Time frame
Primary end point(s): Achievement of full enteral feeds. Development of Necrotising Enterocolitis. ; Main Objective: To shorten the time to first achievment of full enteral feeding and so reduce the risk associated with parenteral feeding. ; Secondary Objective: Secondary research questions: Is the use of glycerine suppositories associated with a decrease in - NEC, - Sepsis, - Oxygen requirement, - Episodes of abdominal distension, or an increase in rate of growth?	—

Measure

Time frame

Primary end point(s): Achievement of full enteral feeds. Development of Necrotising Enterocolitis. ; Main Objective: To shorten the time to first achievment of full enteral feeding and so reduce the risk associated with parenteral feeding. ; Secondary Objective: Secondary research questions: Is the use of glycerine suppositories associated with a decrease in - NEC, - Sepsis, - Oxygen requirement, - Episodes of abdominal distension, or an increase in rate of growth?

—

Countries

United Kingdom

Outcome results

None listed

Source: EU CTR (via WHO ICTRP) · Data processed: Feb 4, 2026